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Biomedical subjects

Z Wajima

Publications and source records attributed to Z Wajima.

26 records · Page 2Linked to original sources
PubMed1995

[A case of atopic dermatitis treated with stellate ganglion block--the change of serum IgE and blood eosinophil levels].

Stellate ganglion block (SGB) therapy was tried on a patient with severe adult type atopic dermatitis. SGB was performed 102 times in total and clinical symptoms improved gradually. Serum IgE and blood eosinophil levels, which correlate with disease severity, increased gradually following repeated SGB. After a series of SGB was stopped, clinical symptoms became worse and serum IgE and blood eosinophil levels increased again. We conclude that although SGB is presumably one of the effective therapies for severe adult type atopic dermatitis, it might be difficult to improve atopic constitution entirely because the patient was not cured completely following repeated SGB.

Adult↗
PubMed1995

[A case of using continuous double-tapped epidural analgesia for herpes zoster duplex].

A 66-year-old woman developed herpes zoster duplex, which is a rare disease. She had severe pain at the right upper back area and left lower abdominal area. The authors used double-tapped continuous epidural analgesia for this patient. The catheters for the epidural block were placed at the 8th thoracic vertebral level and 2nd lumbar vertebral level. After the start of continuous epidural block, she suffered from nausea, vomited, and felt dizzy. It was evident that these symptoms were caused by local anesthetic toxicity. We emphasize that we must pay attention to the patient who undergoes continuous double-tapped epidural analgesia for pain relief so as not to elicit local anesthetic toxicity.

Aged↗
PubMed1995

[Changes in dementia rating scale scores of elderly patients with femoral neck fracture during perioperative period].

We evaluated changes in dementia rating scale scores in the revised version of Hasegawa's dementia scale (HDS-R), and rated dementia, 2 days before and 7 days after surgery in the elderly patients with femoral neck fracture. The 50 patients examined ranged in age from 70 years to 101 years. A perfect score in the HDS-R is 30 points, and a score below 20 points strongly suggests dementia. The results were as follows. In septuagenarian and octogenarian patients, the scale score was higher after surgery than the value before the surgery. Although the preoperative and postoperative scores of the patients who had been under epidural anesthesia were not significantly different, the score of patients who had been under general anesthesia was higher in the postoperative period than in the preoperative period. In octogenarian patients, there was a negative correlation between "postoperative score minus preoperative score" and "the number of the days from suffering fracture to surgery". These results showed that general anesthesia is more advantageous than epidural anesthesia from the viewpoint of the intellectual faculty in septuagenarian and octogenarian patients with femoral neck fracture, and it is within the bounds of possibility that the intellectual faculty may decline if an octogenarian patient is operated after a long delay from the occurrence of fracture. To prevent this decline, patients must be operated on as soon as possible.

Age Factors↗
PubMed1993

The effects of an intravenous nicardipine injection on baroreflex control of heart rate in man.

The effects of nicardipine injection on baroreflex control of heart rate were investigated by both pressor and depressor tests in 17 adult patients. Baroreflex sensitivity was attenuated after nicardipine injection by the pressor test using phenylephrine, whereas it was not changed by the depressor test using nitroglycerine. No resetting of the baroreflex occurred after nicardipine injection. By the pressor test, the plasma norepinephrine level was decreased, indicating that parasympathetic activity increased, and by the depressor test, the plasma norepinephrine concentration was increased, indicating that sympathetic activity increased. These results suggest that it is safe to use nicardipine clinically even when reduction in blood pressure for hypovolemia or unclamping the main artery is expected, and it is disadvantageous to administer the drug when an increase in blood pressure due to cross-clamping of the main artery is forecasted.

Journal Article↗
PubMed1993

The effects of butorphanol on baroreflex control of heart rate in man.

The effects of butorphanol injection on baroreflex control of heart rate were investigated using both pressor and depressor tests in eighteen adult patients. Baroreflex sensitivity was attenuated after butorphanol injection in the pressor test using phenylephrine, whereas it was unchanged in the depressor test using nitroglycerine. No resetting of the baroreflex occurred after butorphanol injection. After the administration of butorphanol, plasma epinephrine and norepinephrine levels increased. These results suggest that it is safe to use butorphanol clinically even when a reduction in blood pressure due to hypovolemia or unclamping of the major artery is expected and that it is disadvantageous to administer the drug when an increase in blood pressure due to cross-clamping of the major artery is predicted.

Journal Article↗
PubMed1993

[The effects of intravenous lidocaine on baroreflex control of heart rate in man].

The effects of intravenous lidocaine on arterial baroreflex control of heart rate were investigated using both the pressor and depressor tests in 16 adult patients. Baroreflex sensitivity was unchanged 5 and 20 minutes after lidocaine 1.5 mg.kg-1 bolus injection according to the results of both the pressor and depressor tests. Resetting of the baroreflex, tachycardia and increased blood pressure were also observed after lidocaine injection. Clinically the results obtained in the present study suggest that it is safe to use lidocaine even when reduction of blood pressure by hypovolemia or declamping the main artery is expected and when a rise in blood pressure due to cross-clamping of the main artery is foreseen. However, intravenous lidocaine tended to produce tachycardia, and baroreflex sensitivity was unchanged after lidocaine injection according to the results of the depressor test. This means that tachycardia readily occurs during hypotension. This may suggest that intravenous lidocaine is not always advantageous for patients with ischemic heart disease.

Adolescent↗
PubMed1991

Large dose of flunitrazepam attenuates baroreflex control of heart rate in man.

The effects of intravenous tranquilizers such as flunitrazepan, diazepam and droperidol on baroreflex control of heart rate were investigated using both pressor and depressor tests. The dose-dependency was also studied by the administration of the drugs at the usual or twofold dosage. The usual dosage caused no significant change in neuronal controlling mechanism of circulation. However, flunitrazepam at double the usual dosage produced a decrease in baroreflex sensitivity at depressor tests. The results suggest that flunitrazepam when given repeatedly might accelerate hemodynamic derangements induced by an acute decrease in blood pressure.

Journal Article↗