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Zafar Ahmed

Publications and source records attributed to Zafar Ahmed.

5 recordsLinked to original sources
PubMed2005

Over-under myringoplasty.

OBJECTIVE: To determine the success rate of over-under technique of myringoplasty regarding rate of graft take, complications and hearing improvement. DESIGN: Quasi-experimental study. PLACE AND DURATION OF STUDY: Department of Otorhinolaryngology and Head and Neck Surgery, Fauji Foundation Hospital, Rawalpindi from March 2003 to January 2005. PATIENTS AND METHODS: A total of 68 patients having dry central tympanic membrane perforations of various sizes secondary to chronic tubotympanic suppurative otitis media were included in the study. Over-under technique of myringoplasty was used to repair the tympanic membrane perforation. Outcome measures were graft success i.e., full or partial take, no perforation, atelactasis or lateralization within 6 months of operation and improvement in hearing. RESULTS: Sixtysix patients (97%) out of 68 had full graft take at six months of follow-up. Only one (1.5%) met with graft failure and another one (1.5%) had partial graft take. Delayed perforation was noted in two patients (3%), both of these were 10 months after surgery. Atelactasis was seen in only one patient (1.5%) eight months after operation. Lateralization did not occur in any patient. Hearing improvement was noticed in 67 (98.5%) patients. Average air bone gap decreased by 12.65 dB. CONCLUSION: Over-under myringoplasty is an effective technique of repairing the tympanic membrane perforation due to high rate of graft take, few complications and marked hearing improvement.

Adolescent↗
PubMed2004

Microbiology and drug sensitivity patterns of chronic suppurative otitis media.

OBJECTIVE: To identify the commonest microorganisms associated with chronic discharging ears and their antimicrobial sensitivities. DESIGN: Descriptive study. PLACE AND DURATION OF STUDY: This study was carried out from August 2003 to February 2004 at the Department of Otorhinolaryngology and Head and Neck Surgery, Fauji Foundation Hospital, Rawalpindi. MATERIALS AND METHODS: A total of 124 patients with unilateral or bilateral active chronic suppurative otitis media attending the outpatient clinic were included in the study. All patients were evaluated through detailed history and clinical examination. Pus samples were collected from the discharging ear(s) and sent to the hospital laboratory where culture and sensitivity studies were done for aerobes, anaerobes and fungi and antibiotic sensitivity patterns. RESULTS: Overall microbiology of 142 samples was studied. Among them, 108 (76%) were pure cultures and 34 (23.9%) were mixed. There were 186 isolates including 182 (97.8%) aerobes, nil anaerobes and only 4 (2.1%) fungi. Pseudomonas aeruginosa 94(50.5%) was the most common isolate, followed by Staphylococcus aureus 44 (23.6%). Drug sensitivities pattern of Pseudomonas aeruginosa showed that ciprofloxacin was active against majority 95.8% of isolates followed by amikacin 83.3%, gentamicin and tobarmycin 60% and cefotaxime 41.6%. Staphylococcus aureus isolates were resistant to penicillin, ampicillin and amoxicillin in 77.2% whereas majority was sensitive to coamoxiclav 81.8% and cephradine 86.3%. CONCLUSION: Commonest organisms isolated from chronic discharging ears were Pseudomonas aeruginosa and Staphylococcus aureus. Majority of isolates of Pseudomonas aeruginosa were sensitive to ciprofloxacin. Majority of strains of Staphylococcus aureus were resistant to penicillin. Cephradine and coamoxiclav were effective against most of the isolates of Staphylococcus aureus.

Adolescent↗
PubMed2003

Pseudounitary symmetry and the Gaussian pseudounitary ensemble of random matrices.

Employing the currently discussed notion of pseudo-Hermiticity, we define a pseudounitary group. Further, we develop a random matrix theory that is invariant under such a group and call this ensemble of pseudo-Hermitian random matrices the pseudounitary ensemble. We obtain exact results for the nearest-neighbor level-spacing distribution for (2 x 2) PT-invariant Hamiltonian matrices that have forms, approximately Sln(1/S) near zero spacing for three independent elements and approximately S for four independent elements. This shows a level repulsion in a marked distinction with an algebraic form S(beta) in the Wigner surmise. We believe that this paves the way for a description of varied phenomena in two-dimensional statistical mechanics, quantum chromodynamics, and so on.

Journal Article↗
PubMedDate not supplied

Biotransformation of (-)-a-pinene by Botrytis cinerea.

(-)-alpha-Pinene (1), a major constituent of many aromatic plants was biotransformed by the plant pathogenic fungus, Botrytis cinerea to afford three new metabolites, characterized as 3beta-hydroxy-(-)-beta-pinene (10%) (3), 9-hydroxy-(-)-a-pinene (12%) (4), 4beta-hydroxy-(-)-alpha-pinene-6-one (16%) (5) by physical and spectroscopic methods. A known metabolite verbenone (2) was also obtained.

Bicyclic Monoterpenes↗