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Biomedical subjects

Zbigniew Bednarkiewicz

Publications and source records attributed to Zbigniew Bednarkiewicz.

4 recordsLinked to original sources

Elderly and patients with sick sinus syndrome have lower chances for appropriate pacemaker mode selection, according to the Polish Cardiac Society recommendations -- a single-centre retrospective analysis.

BACKGROUND: The Polish Cardiac Society recommendations for permanent heart pacing have been valid since 1999. The clinical use of these guidelines is, however, still limited. AIM: To analyse whether the chosen pacing strategy is consistent with the Polish Cardiac Society recommendations and to estimate the effects of analysed factors on selecting optimal or suboptimal pacing modes. METHOD: Retrospective analysis of medical records and procedure protocols of 1052 patients who underwent pacemaker implantation between 1 January 2000 and 31 December 2004 was performed. In each case, the applied pacing mode was compared against the optimal one defined according to the guidelines of the Polish Cardiac Society. A number of demographic and clinical factors associated with the procedure were analysed and correlated with the optimal pacing mode selection. RESULTS: During the analysed period, 59.3% of patients received optimal pacing. The percentage of patients with optimal pacing increased in the consecutive years from 40.2% in 2000 to 68.5% in 2005. In a univariate regression analysis, patients above the age of 70 years, with sick sinus syndrome as an indication for pacing, as well as cardiac heart failure and obesity, received optimal pacing significantly less frequently. In a multivariate analysis, advanced age and sick sinus syndrome were found to be independent predictors of suboptimal pacing. CONCLUSIONS: About 60% of patients had their pacemakers implanted with the optimal pacing mode selection according to the valid recommendations. Patients over the age of 70 years, as well as patients with sick sinus syndrome, had significantly lower chances of receiving optimal pacing.

Age Distribution↗

[Transient psychiatric abnormalities in patients with acute myocardial infarction].

UNLABELLED: Psychiatric abnormalities (PA) are often observed in patients (pts) in the Coronary Care Units. The origin of such abnormalities is not always clear, but it is known that they may aggravate patients status and interfere with further treatment. The aim of this study was to analyze the factors potentially predisposing to the occurrence of PA in pts with acute myocardial infarction (AMI). MATERIAL: The study group consisted of 200 consecutive pts hospitalized due to AMI. In 63 of them (Group A) the in-hospital course was complicated by PA (agitation, anxiety, hallucinations). Sex- and age-matched 63 pts of the remaining 137 pts which had not PA were control group (Group B). METHODS: The data related to coronary artery disease history, AMI diagnosis and treatment were withdrawn from hospital reports. Second group of parameters was focused on history of central nervous system (CNS) diseases, vision and audition ability, stimulant or drug addiction. The data about patient's employment and familial status, level of education, self-estimation of quality of life (QoL) in hospital were the third group of parameters. The second and third group of data were questionnaire-based information. RESULTS: There were no significant differences between groups in arrhythmias, localization of AMI, percentage of pts with high level of education, neither living alone or with family, jobless, retired or employed ones. Also self-evaluation of QoL was distributed similarly. The parameters which differed Group A versus Group B were respectively: history of CNS diseases (48% vs 20%, p<0,05), in particular--CNS traumas (18% vs 2,3%, p<0,05) and ischemic episodes (10% vs 0%, p = 0,039), thrombolytic (non-percutaneous interventional) treatment 23,8 vs 4,6%, p<0,05), handicap of visual ability (16% vs 0%, p--0,012), nicotinism (30% vs 9,1%, p<0,05), left ventricle ejection fraction <40% (34% vs 5%, p<0,05), treatment with atropine (12,7% vs 0%, p = 0,012) or amiodarone (16,7% vs 0%, p = 0,037). CONCLUSION: History of neurological diseases, thrombolytic treatment, left ventricle ejection fraction <40%, handicap of visual ability, nicotinism and amiodarone or atropine in pharmacological treatment are factors which may be helpful to predict PA in pts with AMI. Cumulation of such factors increases a risk of occurrence of transient psychiatric abnormalities. Proper psychoactive pretreatment should be applied in pts with such profile in purpose to avoid behavior related complications.

Adult↗

[Persistent left superior vena cava].

Persistent left superior vena cava -- a case report. A case of a 72-year-old female admitted for pacemaker implantation is presented. During the procedure, persistent left superior vena cava was found. Pacemaker was inserted via right subclavicular vein.

Aged↗

Myocardial ischemia and autonomic activity in dippers and non-dippers with coronary artery disease: assessment of normotensive and hypertensive patients.

OBJECTIVES: The aim of this study was to assess the relations between the circadian variations of blood pressure (BP) and the pattern of ischemia and autonomic activity in normotensive and hypertensive patients with coronary artery disease (CAD). PATIENTS AND METHODS: On the basis of the results of ambulatory BP monitoring, 115 patients with stable CAD were divided into Group 1 (with arterial hypertension) and Group 2 (normotensives). Groups were subdivided into dippers and non-dippers. Holter monitoring was performed to assess the occurrence and circadian pattern of ischemic episodes. Time domain and frequency domain HRV analyses were performed to evaluate the autonomic activity. RESULTS: The total number of ischemic episodes was similar in dippers and non-dippers. Non-dippers had a greater number of silent episodes and a different circadian pattern of ischemia with more night episodes. Among the time-domain HRV parameters, only SDNN was similar in dippers and non-dippers. Non-dippers had lower pNN50 and rMSSD-the parameters expressing parasympathetic activity. Differences between diurnal and nocturnal results of spectral HRV analysis were observed in dipper patients only. They presented an elevation of HF power and a decline of LF power at night. All differences between dippers and non-dippers were of similar significance in both hypertensives and normotensives. CONCLUSIONS: A lack of a nocturnal fall in BP is present in normotensive and hypertensive patients with CAD. Non-dippers with CAD had silent and nighttime ischemia more often. They also had an abnormal pattern of autonomic activity with higher sympathetic and lower parasympathetic modulation.

Analysis of Variance↗