Biomedical subjects
Publications and source records attributed to Zhen Yang.
Two types of quinoline scaffolds were constructed in a combinatorial format via the Ugi four-component reaction (U-4CR) and Pd-catalyzed intramolecular arylation reaction. The scope of this two-step synthetic sequence was examined from commercially available and synthetically accessible starting materials.
BACKGROUND/AIMS: To investigate the diagnostic accuracy of ultrasonography for regional portal hypertension (RPH) and ascertain the best diagnosis method for RPH. METHODOLOGY: Eleven cases of regional portal hypertension diagnosed by ultrasonography were retrospectively studied. Their etiological features, clinical findings, and ultrasonographic diagnosis criteria were analyzed. Other diagnostic approaches were also compared and related literature was reviewed. RESULTS: Eleven patients were all verified by operation. The diagnostic accuracy of color Doppler ultrasonography was 100%. The etiological diagnostic accuracy was 91% (10/11). CONCLUSIONS: Color Doppler ultrasonography should be considered as the first choice to diagnose RPH due to its safety, accuracy, and simplicity. RPH can be classified etiologically into 3 types: pancreatic RPH, splenic RPH, retroperitoneal RPH.