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Biomedical subjects

Zhen-kang Zhang

Publications and source records attributed to Zhen-kang Zhang.

12 recordsLinked to original sources

[Diagnosis and management of 49 cases of hemangiomas in infants and children].

OBJECTIVE: To observe the management results of hemangioma in infants and children. METHODS: Forty-nine cases of hemangioma in infants and children managed from 1986 to 2004 were reviewed. During the management period, the incidence and first visit age and sex were recorded. The location and volume of the lesions were photographed and followed up at an interval of 3 to 12 months until the complete involution of the tumor. The treatment modalities used included local injection of prednisone in 16 cases, surgery in 6 cases, and the remaining 33 cases were observed without treatment. RESULTS: Thirty-three cases receiving no treatment involuted naturally. The complete involution age was found from 9 months to 10 years with average age of 5.4 years. The cosmetic results after involution were good. CONCLUSIONS: Most hemangiomas do not need treatment and can involute naturally. However, in cases with severe complications such as expansion, destruction and obstructive or congestive heart failure, treatment is indicated.

Child↗

[A primary research on the concomitant symptoms of temporomandibular joint pain].

OBJECTIVE: To investigate the states of chronic symptoms of other parts of the body concomitant with temporomandibular joint (TMJ) pain. METHODS: Fifty-one patients with TMJ pain and thirty-one control subjects without TMJ symptoms were chosen randomly. The TMJ symptoms and chronic symptoms of other regions were investigated at the base line. The TMJ pain patients were investigated again half year after treatment. Between-symptom correlations were analyzed using linear regression and Chi-squared analysis method (alpha = 0.05). RESULTS: The chronic symptoms related to the TMJ pain at the base line were headache, back pain, numbness of hand, neck and shoulder pain, insomnia, dizziness, reduced hearing ability, eye pain and fatigue (P < 0.05). The incidences of the symptoms of patients were higher than those of the control subjects (P < 0.01). Half year later, the headache, neck and shoulder pain and fatigue were the symptoms improved with the TMJ pain treatment (P < 0.05). CONCLUSION: The symptoms of adjacent regions of orofacial area such as neck and shoulder pain and headache are the main concomitant symptoms of the TMJ pain, and these symptoms may be improved by the treatment of TMJ.

Adolescent↗

[Hemimasticatory muscle spasm: an electromyogram analysis].

OBJECTIVE: To investigate the usefulness of electromyogram (EMG) in the diagnosis of the patients with hemimasticatory spasm (HMS). METHODS: Four cases with HMS were reported. All the 4 patients were undertaken needle and surface electrode EMG examination. RESULTS: Needle electrode EMG of the 4 patients with HMS showed grouped potentials synchronously with the onset of the spasm, which indicated abnormal excitatory electrical activities of the trigeminal nerve resulting in involuntary masticatory muscle movements. CONCLUSION: It is very important to use EMG for the diagnosis of HMS.

Adult↗

[A study on the classification and treatment of zygomatic complex fractures].

OBJECTIVE: To investigate a new classification and treatment of zygomatic complex fractures (ZCF) by clinical and radiographic studies. METHODS: Standard radiographs with Waters, submental vertex views had been obtained before and after operation in 206 patients (212 sides) with ZCF. Patients with complicated fractures underwent two and three dimensional CT. Computer-assisted measuring system was used to measure the degree of displacement. RESULTS: ZCF were classified into 3 types and 6 subtypes according to the degree of displacement of segments and facial deformities. Treatment principles were proposed. The results were satisfied through clinical application and measurement of post-operative images. CONCLUSIONS: The treatment for ZCF should be selected according to the fracture types. The key of operation is to recover the malar prominence. Remodeling the length and radian of zygomatic arch guarantee the recovery of malar prominence. Zygomatic-sphenoid and zygomatic-maxillary fissures are very important reference marks for reduction and fixation.

Adolescent↗

[Application of the nasal lining flap to correct the wide unilateral complete cleft lip].

OBJECTIVE: To study use of nasal lining flap in correction of the wide complete unilateral cleft lip. METHODS: 78 patients with wide complete cleft lip were. operated, firstly to be sure. That the lip length on both sides was equal. Then the nasal lining flap was used to enhance the height of the lip on cleft side for keeping symmetry with the non-cleft side. The rest of procedures was the same as "Millard" method. RESULTS: 84.6 percent of patients had good appearance at one and half years after surgery. CONCLUSIONS: It is an effective way to take advantage of the nasal lining flap to correct the wide complete unilateral cleft lip.

Cleft Lip↗

[The influence of the osteogenesis in cleft palate after palatal surgery to the transverse growth of dental occlusion].

OBJECTIVE: To compare the transverse growth of the dental cast following palatal surgery with or without osteogenesis in palatal gap. METHODS: 31 patients at 13 - 28 years old with repaired palate were selected to take the dental cast, the width of the dental arch, alveolar base and the matching degree between arches were measured and the average was calculated. After the length of the bone bridge in palate was measured through CT scan, the relationship between the osteogenesis in palatal gap and the transfers growth of dental cast was studied. RESULTS: The critical length of the bone regeneration in palatal gap to affect the dental growth is 4 mm, mean while the sufficient length is 8 mm. The group of sufficient bone bridge has a better development in both the width of dental alveolar base and that of dental arch and the matching degree than the group of unsurficience. And this intendance was more obvious in premolar region than in molar region. CONCLUSIONS: The osteogenesis in palatal gap following palatal surgery can strongly support the transfers growth in the width of dental arch, the width of alveolar base and the matching degree between upper and lower dental arch.

Adolescent↗

[Disc-like changes and type II collagen mRNA expression in the bilaminar zone of rabbit temporomandibular joint following disc displacement].

OBJECTIVE: To study the adaptive alteration in bilaminar zone of rabbits' temporomandibular joint following disc displacement. METHODS: Twenty-six Japanese white rabbits were used in this study. Among these rabbits,6 were used as controls. The right discs of other 20 rabbits were displaced anteriorly by operation. Four of these rabbits were killedatn 1, 2, 4, 6 and 8 weeks respectively after surgery. The TMJS were studied by HE staining, Alcin bluen staining and in situ detection of type II collagen mRNA expression. RESULTS: There appeared cartilage metaplasia after one week following disc displacement. Typical chondrocytes could be found in the bilaminar zone. The new chondrocytes expressed type II collagen. CONCLUSIONS: The bilaminar zone of TMJ will be remodeled following disc displacement and become a disc-like tissue to function as a disc.

Animals↗

[Bone regeneration on hard palate after palatal surgery on cleft palate and the relative factors].

OBJECTIVE: Attending to observe the bony healing on hard palate after palatal repair, and to discuss the factors affecting on it. METHODS: 52 patients with repaired cleft palate over 5 years postoperatively were examined, the CT scan of head was taken. The incidence of the bone regeneration among the patients examined was calculated, the position and quality of bone tissue were measured according to the CT images. After all, analysis was applied to evaluate the factors affecting on the bone tissue formation. RESULTS: Formation of bone bridge was found in the 37 cleft gaps out of 52 patients (71%), the ratio of the sex among the patients who had bone bridge was 1:1, there was no obvious difference between unilateral and bilateral cleft palate. Considering the operation age with the bone formation, the highest percentage of bone bridge formation fell into the group of 4-7 years old, and the most occurring region were in premolar and anterior part of molar area. CONCLUSION: There could be bony healing(regeneration bone tissue RBT) after palatal repair on cleft palate patients. The operation age could be an important affecting factor to RBT, but the sex and the clinical type of cleft palate make no difference on the bone tissue formation.

Age Factors↗

Factors influencing postoperative satisfaction of orthognathic surgery patients.

The purpose of this study was to investigate the postoperative satisfaction of orthognathic surgery patients and related factors. The authors assessed 108 orthognathic surgery patients using the Minnesota Multiphasic Personality Inventory and the Symptom Checklist 90 preoperatively. The degree of deformity, expectations for surgery, and support of significant others were also evaluated before surgery. The patients were given questionnaires at 4 time points, from 10 days to 1 year after surgery. A multiple regression test was used to analyze the relative importance of psychologic factors and other variables in explaining the degree of patients'satisfaction with surgery. Postoperative satisfaction was high and increased with time. Patients with more education and more severe deformities reported greater satisfaction. During the early stage after surgery, patients with a high degree of interpersonal sensitivity, whose close relatives did not support surgery, or who accepted surgery passively tended to be more dissatisfied. Patients who had realistic expectations were more satisfied in the long term. Complications such as pain and swelling influenced patients' satisfaction soon after surgery, whereas the responses of people around the patients influenced their satisfaction at all stages postoperatively.

Adolescent↗