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Zheng-shan Chang

Publications and source records attributed to Zheng-shan Chang.

14 recordsLinked to original sources

[Amiodarone pneumonitis with Hypermastigote lung infection: a case report and review of the literatures].

OBJECTIVE: To describe the clinical features of amiodarone pneumonitis with Hypermastigote lung infection. METHODS: Case report and review of the related literatures. The clinical symptoms, laboratory tests, radiographic patterns, diagnosis, and therapeutic management of amiodarone pneumonitis with Hypermastigote lung infection were described. RESULTS: A 58 year old male patient presented dyspnea after exertion. Pulmonary function showed decrease of the diffusing capacity, and CT showed interstitial changes and alveolar exudation. Foamy cells and Hypermastigotes were found in the bronchoalveolar lavage fluid. After cessation of amiodarone and the start of anti-parasite therapy, the symptoms relieved. CONCLUSIONS: Amiodarone pneumonitis with Hypermastigote lung infection is very rare. The infection may be due to decrease of local immunity caused by amiodarone pneumonitis.

Amiodarone↗

DNA sequences of Paragonimus skrjabini populations from five provinces in China.

BACKGROUND: To study differences among Paragonimus skrjabini (P. skrjabini) populations from five provinces in China (Guangdong, Fujian, Yunnan, Hubei, and Sichuan) and Paragonimus szechuanensis. METHODS: DNA sequences were obtained from the ITS2 and CO1 genes and phylogenetic trees were constructed from the results. Sequences were also obtained from several other species of Paragonimus for comparative purposes. RESULTS: Although differences existed in the DNA sequence among P. skrjabini populations from five provinces, the differences were very small. There was also some resemblance between P. miyazakii from Japan and Fujian strains of P. skrjabini. CONCLUSION: All studied populations can be regarded as different strains of P. skrjabini; P. szechuanensis is not a separate species but may be a geographical strain of P. skrjabini. We also found that P. miyazakii may be synonymous with P. skrjabini.

Animals↗

[Taxonomic status in DNA sequences of five species of genus Paragonimus].

OBJECTIVE: To analyze the taxonomic status of Paragonimus hokuoensis, P. paishuihoensis, P. menglaensis, P. bangkokensis and P. xiangshanensis in Genus Paragonimus Braun, 1899. METHODS: DNA sequences were obtained from the ITS2 and CO I genes and phylogenetic trees were built from these. RESULTS: There are some DNA sequence differences among P. paishuihoensis, P. menglaensis, P. bangkokensis and P. xiangshanensis, but the differences are small. P. hokuoensis and P. skrjabini are similar in DNA sequence. CONCLUSION: P. paishuihoensis, P. menglaensis, P. bangkokensis and P. xiangshanensis are closer in the genetic relationship. Their taxonomic status lies between P. skrjabini and P. westermani. The genetic relationship between P. hokuoensis and P. skrjabini is very close.

Animals↗

[Study on DNA sequences of Paragonimus skrjabini populations from five provinces in China].

OBJECTIVE: To study differences among Paragonimus skrjabini populations from five provinces (Guangdong, Fujian, Yunnan, Hubei, Sichuan) and Paragonimus szechuanensis and to analyze the taxonomic status of P. heterotremus and P. veocularis in the Genus Paragonimus Braun, 1899. METHODS: DNA sequences were obtained from the ITS2 and CO1 genes and phylogenetic trees were built. RESULTS: Difference of the DNA sequences among P. skrjabini populations from five provinces were minor. P. veocularis and P. skrjabini were similar in DNA sequences. There were also some resemblances between P. miyazakii from Japan and the Fujian isolates of P. skrjabin. In addition, P. heterotremus was found to be closer to P. skrjabini and quite a distance from P. westermani in the phylogenetic tree. CONCLUSION: All studied populations can be regarded as different strains of P. skrjabini; P. szechuanensis is not a separate species, but possibly a geographical strain of P. skrjabini. Also found was that P. veocularis and P. miyazakii may be the synonyms of P. skrjabini. As a separate species, P. heterotremus was found to be closer to P. skrjabini and quite a distance from P. westermani in the genetic relationship.

Animals↗

[Improvement in the preparation of Paragonimus westermani chromosome for karyotype analysis].

OBJECTIVE: To improve Paragonimus westermani chromosome preparation technique. METHODS: After being exposed to colchicine, the gonadal cells of P. westermani were treated by the following procedures: hypotonicity, fixation, dropping onto a slide and staining. RESULTS: The chromosome number of P. westermani is 22, and the karyotype is 2m + 6Sm + 14t chromosome. CONCLUSION: The improved technique of chromosome preparation is feasible to operate and the chromosome is clear enough for karyotype analysis.

Animals↗