Biomedical subjects

Zhibin Zhou

Publications and source records attributed to Zhibin Zhou.

3 recordsLinked to original sources

PubMed2003

Relationship between levels of serum C-reactive protein, leucocyte count and carotid plaque in patients with ischemic stroke.

In order to study the relationship between serum C-reactive protein (CRP) levels, leukocyte count and carotid plaque in patients with ischemic stroke, carotid duplex examination was performed by high-definition imaging (HDI) 5000 triplex system. Serum CRP was measured by nephelometry within 72 h after index ischemic stroke. A lesion was considered a plaque in the presence of a maximum intimal-medial wall thickness (IMT) 1.2 mm. Results of carotid ultrasonography were divided into two groups: M1, normal (IMT < 1.2 mm) and M2, abnormal (IMT > or = 1.2 mm). The results showed that the mean age of M2 was significantly older than that of M1 (69.7 +/- 10.4 versus 62.5 +/- 9.6, P = 0.001). The patients with hypertension and diabetes mellitus (78%, 35% respectively) in M2 were significantly more than those (52%, 18% respectively) in M1 (P < 0.01, P < 0.05). There were 32 (65%) patients with elevated CRP levels in M2, but 33 (46%) patients with elevated CRP levels in M1, with the difference being significant between the two groups (P < 0.05). The levels of serum glucose and leukocyte count (8.1 +/- 5.5, 10.3 +/- 4.0, respectively) in abnormal CRP group were significantly higher than that of normal CRP group (6.4 +/- 2.8, 8.7 +/- 3.4) (P < 0.05, P < 0.05); elevated CRP levels was found in 42 (62%) patients with territory infarction and 23 (43%) patients with lacunar infarction respectively, with the difference being significant between these two groups (P < 0.05). It was concluded that the elevation of CRP levels was an significant clinical index for carotid plaque in patients with acute cerebral infarction.

Adult↗

PubMed2003

[Ecological distribution of soil microorganism in artificial greenbelt in hinterland of Takilimakan Desert and their relations with soil factors].

Studies on the distribution of soil microorganisms in the artificial greenbelt in hinterland of Takilimakan Desert and the effects of soil features on the distribution showed that under saline water irrigation, the activities of soil microorganisms increased sharply, and the soil structure and nutrient status were improved. Among soil microorganisms, bacteria were predominant, actinomyces were the next, and fungi were the least. There were more microorganisms in upper than in deeper soil layers. Soil microorganisms near shelter-forest had a higher activity, and their quantities over 3 m from shelter-forest were almost equal to those in shifting sand. The quantities of soil microorganisms varied with seasons, and there were distinct differences among different sites of forests. Among the measured 11 soil factors, the interactions between pairs of soil available phosphorus-available potassium, organic matter-available potassium, available nitrogen-available potassium, available nitrogen-available phosphorus, organic matter-available phosphorus, available phosphorus-available nitrogen, total nitrogen-available potassium, available potassium-available phosphorus, total nitrogen-available phosphorus, and water contents-available nitrogen were significant, with the correlation coefficients of 1.37-2.58. The direct effects of available phosphorus, available nitrogen, and total nitrogen on the microbial quantity were significant, with the coefficient of 1.01-2.58.

Conservation of Natural Resources↗

PubMed2003

[Basic study of biodegradable controlled release chemotherapy].

This study sought to assess the biocompatibility of P(DA-SA)-Adriamycin, a new controlled-release chemotherapy system, in rabbit brain, and to examine its controlled release effect both in vitro and in vivo and its curative effects in vitro. The reaction of animal brain to the implanted P(DA-SA) or P(DA-SA)-Adriamycin was observed. The controlled-release profiles in phosphate buffer solutions and in rabbit brain were measured by UV spectrometry. Then, through flow cytometer, the rate of apoptosis in cultured glioma cells was tested. The reaction of rabbit brain to P(DA-SA) polymer was moderate and not significantly different from that to Gelfoam. The controlled-release rate of P(DA-SA)-Adriamycin in vitro and in vivo was stable and the duration of controlled-release of P(DA-SA)-Adriamycin spanned three weeks. The rate for apoptosis of glioma cells of P(DA-SA)-Adriamycin group was 69.9%, which was significantly higher than that of the control group. In conclusion, P (DA-SA)-Adriamycin controlled release chemotherapy system that bears curative effect has favorable controlled-release effect and good biocompatibility in rabbit brain. This system has potential value in treatment of malignant brain tumor.

Animals↗