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Biomedical subjects

Zhoujun Shen

Publications and source records attributed to Zhoujun Shen.

4 recordsLinked to original sources

[Erectile function evaluation after adult circumcision].

OBJECTIVE: To evaluate the erectile function of adults after circumcision. METHODS: Ninty-five patients were investigated on erectile function by questionnaire before and after circumcision, respectively. RESULTS: Eighteen patients suffered from mild erectile dysfunction before circumcision, and 28 suffered from mild or moderate erectile dysfunction after circumcision(P = 0.001). Adult circumcision appeared to have resulted in weakened erectile confidence in 33 cases(P = 0.04), difficult insertion in 41 cases(P = 0.03), prolonged intercourse in 31 cases(P = 0.04) and improved satisfaction in 34 cases(P = 0.04). CONCLUSIONS: Adult circumcision has certain effect on erectile function, to which more importance should be attached.

Adult↗

[Malignant fibrous histiocytoma of the prostate: one case report].

OBJECTIVE: To probe into the diagnosis and treatment of malignant fibrous histiocytoma (MFH) of the prostate. METHODS: One case of MFH of the prostate was diagnosed and treated surgically by radical remocal of the lesion, resection of the rectum and sigmoidoctomy. The clinical features, diagnosis and treatment of MFH of the prostate were reviewed and presented. RESULTS: The patient experienced recurrence 3 weeks after operation, and then underwent radiotherapy. Two months after operation the patient died of metastasis. CONCLUSION: MFH of the prostate has been rare clinically, with poor prognosis. Early and aggressive surgical removal of the primary lesion followed by adjuvant therapy is recommended for the treatment of the disease.

Adult↗

[Clinical significance of six-transmembrane epithelial antigen of the prostate expressed in prostatic carcinoma].

OBJECTIVE: To investigate the relationship between six-transmembrane epithelial antigen of the prostate (STEAP) expression and the histologic grading of prostatic carcinoma (PCa). METHODS: Different prostatic tissues and non-prostatic tumors, 131 cases of PCa, 164 cases of benign prostate hyperplasia (BPH), and 56 cases of non-prostatic malignancies, were analyzed for the expression of STEAP by using STEAP monoclonal antibody and SP immunohistochemical staining. The positive area unit (PU) was introduced to describe the intensity of STEAP expression. RESULTS: The prostatic tissues of all but 3 cases of PCa and 5 cases of BPH were stained positively, while all of the non-prostatic tumors were stained negatively. There was a significant negative correlation between the STEAP expression and the histologic grading of PCa. CONCLUSION: STEAP can be a prognostic marker of PCa and a potential therapeutic target in PCa.

Antigens, Neoplasm↗

[Diagnosis and treatment of tuberculosis in the male genital system].

OBJECTIVE: To probe into and improve the diagnosis and treatment of tuberculosis (TB) in the male genital system. METHODS: Fifteen patients with the male genital system TB established by microbiological and pathological examinations were retrospectively reviewed. RESULTS: The male genital system TB was diagnosed by history, physical examination, semen analysis, TB culture and biopsy. Treatment consisted of antituberculous chemotherapy for all the patients before and/or after operation, including 5 cases of epididymectomy and 6 cases of orchi-epididymectomy. CONCLUSION: The male genital system TB tends to be atypical and semen polymerase chain reaction of TB (TB-PCR) may provide a new specific means for diagnosis in case of clinical suspicion. Surgical approaches should be cautiously adopted, especially for young patients.

Adult↗