Biomedical subjects

Zorica Zivković

Publications and source records attributed to Zorica Zivković.

4 recordsLinked to original sources

PubMedDate not supplied

[Septic arthritis of the hip in infancy--diagnostic and therapeutic possibilities].

Septic arthritis of the hip in infancy is a serious condition which, if left untreated, results in disastrous sequelae and gross invalidity. Treatment is difficult and requires precise perception of characteristic clinical symptoms and signs, application of appropriate diagnostic procedures (laboratory analyses, ultrasound, radiography, joint aspiration, and occasionally additional methods), as well as parenteral administration of adequate antibiotics and obligatory surgical treatment. Differential-diagnostic spectrum of conditions similar to septic hip arthritis is large and diverse. Successful treatment is based on establishing the diagnosis on time, which is only achievable by methodical application of diagnostic protocol for septic hip arthritis in all suspected cases.

Arthritis, Infectious↗

PubMedDate not supplied

[Sequelae of septic hip arthritis in infancy].

Septic arthritis of the hip represents a serious pathological condition which results in severe sequelae and high invalidity. The most serious sequelae are seen in neonatal and infantile period, when normal growth and development are brutally disturbed, followed by proximal femoral destruction and acetabular dysplasia, which in return result in anatomical limb shortening and functional deficiency. In order to achieve an adequate approach to the treatment of septic hip arthritis sequelae, different classification systems have been developed. Two of them are the most cited in literature: classification according to Hunka, and that according to Choi and associates. In this article, the authors compared both classification systems, presented their similarities and differences, and expanded them in view of treatment options applicable to each category. Although both classifications are based on radiographic findings, it has been shown that they clearly tell between treatment options relevant to particular type of sequelae of the septic hip arthritis, thus representing a useful tool in making decision about adequate treatment.

Arthritis, Infectious↗

PubMedDate not supplied

[Graf's method in the ultrasound diagnostics of developmental dislocation of the hip].

The authors present the possibilities of ultrasound diagnostics of developmental dislocation of the hip. Special attention has been paid to Graf's method, originally developed in Austria and Germany that has been introduced in many countries all over Europe, including our country. The method in details, normal and pathological anatomy of the infant's hip, all the sonographic types and subtypes with therapeutic implications were described.

Hip Dislocation, Congenital↗

PubMedDate not supplied

[Ewing sarcoma--current opinion].

Ewing tumor family consists of Ewing tumor of bone, extraosseous Ewing tumor, primitive neurectodermal tumor and Askin tumor. All of them share genetic abnormality, reciprocal translocation (11; 22) (q24; q12), and originate from the same primordial stem cell. Ewing tumor is the most common form, found in 60% of cases. It is the second primary malignant bone tumor. Localized lesion is found in nearly 80% and metastatic disease in 20% of cases. Patients present mostly due to pain and palpable tumefaction, and pathological fracture as the initial problem develops in long bones. Ewing tumor can develop in virtually any bone of the body and in extraosseous localizations as well, while localization in the extremities occurs in 50% of patients. Head or neck localizations are extremely rare. Paraspinal, retroperitoneal or deep pelvic tumor localization is manifested by back pain. Systemic symptoms are also present, commonly fever or weight loss, which often indicates the presence of metastatic disease with predominant invasion of lung, bone and bone marrow. Multimodal chemotherapy with local radiation and/or surgical resection is the best way of modern treatment. Distal parts of extremities and axial skeleton are good prognostic features, while proximal parts, pelvic girdle, metastatic disease and low index of postchemotherapeutic necrosis are associated with poor outcome.

Bone Neoplasms↗