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Biomedical subjects

Zubin Panthaki

Publications and source records attributed to Zubin Panthaki.

3 recordsLinked to original sources

Pediatric breast deformity.

Congenital breast anomalies represent a relatively common set of disorders encountered by pediatric plastic surgeons with a spectrum of severity that ranges widely from the relatively benign polythelia to the very complex disorders such as Poland's syndrome and tuberous breast deformities. While the former can be treated in a single surgical setting with minimal morbidity, the more complicated disorders often require a staged reconstructive algorithm. Some disorders also require a multidisciplinary management for both workup and management. Although rarely a source of functional morbidity, these physical deformities are often a significant source of psychological stress for the adolescent male or female who feels alienated from their peers. The purpose of this article is to review the most common congenital breast disorders including the diagnosis, workup, and management especially the timing of surgical intervention as guided by normal developmental milestones.

Adolescent↗

Perioperative considerations in the autologous breast reconstruction patient with systemic lupus erythematosus.

Following mastectomy, women with breast cancer are faced with choices for reconstruction. In women with systemic lupus erythematosus (SLE), with or without antiphospholipid syndrome (APS), concurrent morbidities are important considerations when deciding the method of reconstruction. The 2 cases we present represent the variable spectrum of SLE and/or APS and their potential complications. When deciding the best course of action, it is most important to consider each case on an individual basis, with important emphasis on preoperative disease status.

Adult↗

Cleft palate and toe malformations in a child with fetal methotrexate exposure.

Methotrexate, a commonly administered chemotherapeutic agent, is a well-known human teratogen. Exposure of a fetus between 6 and 8 weeks of gestation is postulated to cause birth defects. However, fetal exposure to this drug after this critical period is thought to have little to no effect on eventual fetal development and growth. The authors report a case of an infant whose mother was exposed to methotrexate during pregnancy. The infant was evaluated at their clinic for an incomplete cleft palate and associated asymmetric deformities of the toes on both feet.

Antimetabolites, Antineoplastic↗