TY - RPRT TI - Electron-withdrawing substituents decrease the electrophilicity of the carbonyl carbon. An investigation with the aid of (13)C NMR chemical shifts, nu(C[double bond]O) frequency values, charge densities, and isodesmic reactions to interpret substituent effects on reactivity. AU - Helmi Neuvonen AU - Kari Neuvonen AU - Andreas Koch AU - Erich Kleinpeter AU - Paavo Pasanen PY - 2002 DO - 10.1021/jo020121c UR - https://pubmed.ncbi.nlm.nih.gov/12353992/ ID - 12353992 ER -