TY - RPRT TI - Structural perturbation and compensation by directed evolution at physiological temperature leads to thermostabilization of beta-lactamase. AU - Jochen Hecky AU - Kristian M Müller PY - 2005 DO - 10.1021/bi0501885 UR - https://pubmed.ncbi.nlm.nih.gov/16171379/ ID - 16171379 ER -