@misc{indiciae1698ccb957c9, title = {Practical problems in interim analyses, with particular regard to estimation.}, author = {S J Pocock and M D Hughes}, year = {1989}, doi = {10.1016/0197-2456(89)90059-7}, url = {https://pubmed.ncbi.nlm.nih.gov/2605969/}, note = {Source identifier: 2605969} }