@misc{indiciae596cc2b18af7,
  title = {A large increase in enzyme-substrate affinity by protein engineering.},
  author = {A J Wilkinson and A R Fersht and D M Blow and P Carter and G Winter},
  doi = {10.1038/307187a0},
  url = {https://pubmed.ncbi.nlm.nih.gov/6690998/},
  note = {Source identifier: 6690998}
}