Viral effects on antigen processing.

D M Miller; D D Sedmak

doi:10.1016/s0952-7915(99)80017-x

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PubMed · 10047534

Viral effects on antigen processing.

D M Miller·D D Sedmak

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Abstract

Viruses have evolved numerous mechanisms that modulate MHC-mediated antigen presentation, which in turn protect infected cells from T-lymphocyte-mediated immunosurveillance. Recent studies of previously identified viral immunomodulatory proteins reveal the allelic specificity of these proteins, their ability to function in xenogeneic systems and the difficulty in translating in vitro data to in vivo models; moreover, new mechanisms of viral modulation of MHC expression have emerged.

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Animals Antigen Presentation Antigens, Viral Histocompatibility Antigens Class I Histocompatibility Antigens Class II Humans Viruses Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.Review

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D M Miller, D D Sedmak. 1999. Viral effects on antigen processing.. https://doi.org/10.1016/s0952-7915(99)80017-x

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