Crossmodal associative memory representations in rodent orbitofrontal cortex.

P A Lipton; P Alvarez; H Eichenbaum

doi:10.1016/s0896-6273(00)81095-8

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Crossmodal associative memory representations in rodent orbitofrontal cortex.

P A Lipton·P Alvarez·H Eichenbaum

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Abstract

Firing patterns of neurons in the orbitofrontal cortex (OF) were analyzed in rats trained to perform a task that encouraged incidental associations between distinct odors and the places where their occurrence was detected. Many of the neurons fired differentially when the animals were at a particular location or sampled particular odors. Furthermore, a substantial fraction of the cells exhibited odor-specific firing patterns prior to odor presentation, when the animal arrived at a location associated with that odor. These findings suggest that neurons in the OF encode cross-modal associations between odors and locations within long-term memory.

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Animals Association Learning Behavior, Animal Brain Mapping Electrophysiology Frontal Lobe Male Memory Neurons Odorants Olfactory Pathways Rats Rats, Long-Evans Space Perception Journal Article Research Support, U.S. Gov't, P.H.S.

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P A Lipton, P Alvarez, H Eichenbaum. 1999. Crossmodal associative memory representations in rodent orbitofrontal cortex.. https://doi.org/10.1016/s0896-6273(00)81095-8

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