Hepatic lipase.

J Fan; T Watanabe

doi:10.5551/jat1994.5.41

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PubMed · 10077457

Hepatic lipase.

J Fan·T Watanabe

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Abstract

Hepatic lipase (HL) is an important enzyme that is involved in the metabolism of chylomicrons, intermediate density lipoproteins, and high density lipoproteins. HL may affect the liver uptake of remnant lipoproteins by modifying their compositions. HL also participates in the reverse cholesterol transport, thereby influencing the process of atherosclerosis. Several new functions of HL have recently been revealed. In this article, we review some of the recent progress based on studies using transgenic animals, with an emphasis on HL functions in remnant metabolism and atherosclerosis.

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Animals Animals, Genetically Modified Arteriosclerosis Humans Lipase Liver Mice Mice, Transgenic RNA, Messenger Rabbits Conference Proceedings Research Support, Non-U.S. Gov't Review

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J Fan, T Watanabe. 1998. Hepatic lipase.. https://doi.org/10.5551/jat1994.5.41

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