PubMed Health⌕ Search

PubMed · 10148575

Low-temperature sterilization using gas plasmas.

Abstract

A number of plasma-based techniques for sterilizing heat-sensitive medical equipment at low temperatures are being developed worldwide as alternatives to existing chemical and gaseous sterilization methods. The techniques involve the use of plasmas in controlled sterilization processes that increase operator safety and offer medical device manufacturers the option of using materials they cannot currently consider because of the incompatability of those materials with existing sterilization technologies. In this article, the author discusses three development programmes that are under way and assesses the potential applications of the technique as an alternative to ethylene oxide sterilization. The potential of the technique to meet in-house sterilization requirements of medical product manufacturers is also discussed.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

N Griffiths. 1993. Low-temperature sterilization using gas plasmas.. https://pubmed.ncbi.nlm.nih.gov/10148575/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Clonality of clinical methicillin-resistant Staphylococcus epidermidis isolates in a neonatal intensive care unit.

OBJECTIVE: Study of the clonality of methicillin-resistant Staphylococcus epidermidis responsible of epidemic infections in a neonatal intensive care unit. PATIENTS AND METHODS: All S. epidermidis isolates (mecA+) were collected during the epidemic period (December 2003-September 2004) from different pathological products of newborns. Isolates were characterized by genotyping in pulsed-field gel electrophoresis and by electrophoretic profiles obtained by PCR-based analysis of inter-IS256 spacer polymorphisms. RESULTS: Twenty methicillin-resistant S. epidermidis isolates were collected from newborns during the epidemic period and represented 41.6% of the total isolates of S. epidermidis, which is the first Staphylococcus species isolated from the unit. These isolates were collected from blood cultures (80%), vascular catheters (5%), pus (10%), and intra-tracheal tube (5%). Six genotypic profiles were individualized: type A, type B, type C, type D, type E, and type F, with clear dominance of type A. Five different PCR patterns were found with poor correlation to genotypes defined by PFGE. CONCLUSION: Neonatal nosocomial outbreak of methicillin-resistant S. epidermidis was caused by multiple clones of this species with predominance of one epidemic and multiresistant clone. This clone may be transmitted between babies and was able to persist in the unit. PCR IS 256 proved to be less discriminative than PFGE for typing MRSE.

Equipment Contamination↗