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PubMed · 10149310

Diagnostic concepts in open-angle glaucoma.

Abstract

Primary open-angle glaucoma is not yet fully understood in terms of its pathophysiologic mechanisms. However, they are being addressed more completely in the recent literature. To the list of known risk factors associated with this disease, systemic influences are now being added. Primary open-angle glaucoma is becoming a much more complex disease as research uncovers associations and relationships that were previously unknown. Without knowledge of these mechanisms, the clinician is unable to adequately diagnose and treat the problem. Advances in computer-based diagnostic tools have been made, and we are now beginning to understand their value and limitations. However, whatever technology has to offer, we must always remember that the ultimate decision on initial diagnosis and further deterioration remains a clinical one.

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BibTeXRIS

G R Douglas. 1992. Diagnostic concepts in open-angle glaucoma.. https://pubmed.ncbi.nlm.nih.gov/10149310/

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[Implant in Schlemm's canal. A new method for regulating intraocular pressure in patients with primary open-angle glaucoma?].

BACKGROUND: A surgical technique was developed using a Schlemm's canal implant to bypass the obstruction of outflow of the juxtacanalicular trabecular meshwork in patients with primary open-angle glaucoma. The implant device should also bridge healing processes after trabeculotomy and laser techniques. PATIENTS AND METHODS: An 8- to 15-mm-long silicone tube was implanted in each of two human autopsy eyes connecting the anterior chamber directly with Schlemm's canal. Serial sectioning was performed at two sections of 1-mm length. RESULTS: Implantation of the tube was technically uneventful. Histological examination showed no evidence of mechanical disruption of the endothelial lining of the inner wall of Schlemm's canal. CONCLUSION: These preliminary results demonstrate the possibility of shunting aqueous directly into Schlemm's canal using a silicone tube. A clinical study in a selected group of patients is planned.

Glaucoma, Open-Angle↗