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PubMed · 10149969

Skin replacement using collagen extracted from bovine hide.

C J Doillon
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Abstract

This paper reviews the use of biological sponge-shape matrices as dermal replacements in order to orient newly formed wound tissue. Sponge-shape matrices consist of a scaffold made of cross-linked collagen extracted from bovine hide. Other molecules with specific activities on wound tissue ingrowth are bound to collagen. The lamination of sponge with a synthetic material allows this device to be implanted as a temporary skin substitute. For the epidermal cell layer replacement, a biological film-shape matrix can be used in order to cultivate autologous cells during the period that biological sponge-shape matrices are invaded by wound tissue.

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AnimalsBiological DressingsCattleCollagenCross-Linking ReagentsHumansRegenerationWound HealingJournal ArticleResearch Support, Non-U.S. Gov'tReview

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BibTeXRIS

C J Doillon. 1992. Skin replacement using collagen extracted from bovine hide.. https://doi.org/10.1016/0267-6605(92)90099-f

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