Miltefosine: new preparation. Solution for cutaneous application.

PubMed · 10183390

Miltefosine: new preparation. Solution for cutaneous application.

Abstract

In patients with breast cancer and skin metastases, topically applied miltefosine solution yields at least partial regression of the lesions in approximately a quarter of patients when used as an adjunct to standard treatment (surgery, radiotherapy, systemic chemotherapy or hormone therapy) or when standard treatments are contraindicated. Complete remission was achieved in only 6% of cases in non comparative trials, and the median duration before progression resumed was 6 months. Miltefosine can have many local adverse effects.

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Administration, Cutaneous Antineoplastic Agents Blood Cell Count Breast Neoplasms Clinical Trials as Topic Creatine Enzymes Female Humans Middle Aged Nausea Pain Patient Compliance Phosphorylcholine Skin Diseases Skin Neoplasms Treatment Outcome Vomiting Journal Article

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1998. Miltefosine: new preparation. Solution for cutaneous application.. https://pubmed.ncbi.nlm.nih.gov/10183390/

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