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PubMed · 10203705

FHL-1/reconectin: a human complement and immune regulator with cell-adhesive function.

P F Zipfel·C Skerka
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Abstract

A novel regulator of the alternative complement pathway with functions similar to that of factor H has been identified in human plasma. The cDNA encoding this factor H-like protein 1 (FHL-1/reconectin) was isolated several years ago. Here, Peter Zipfel and Christine Skerka describe functional analyses revealing that this novel complement regulatory protein forms a molecular link between immune defense and cell adhesion.

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AnimalsCatalytic DomainCell AdhesionChromosomes, Human, Pair 1Complement Factor HComplement Pathway, AlternativeHumansStreptococcus pyogenesComparative StudyJournal ArticleResearch Support, Non-U.S. Gov'tReview

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P F Zipfel, C Skerka. 1999. FHL-1/reconectin: a human complement and immune regulator with cell-adhesive function.. https://doi.org/10.1016/s0167-5699(98)01432-7

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