Protein folding as a nonlinear nonequilibrium thermodynamic process.

E M Popov

doi:10.1080/15216549900201473

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PubMed · 10204081

Protein folding as a nonlinear nonequilibrium thermodynamic process.

E M Popov

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Abstract

Biofurcational theory of protein folding is developed describing the process of formation of protein native structure as a sequence of non-equilibrium irreversible fluctuations, specific for a particular protein. The model gives explanation to all characteristic features of the folding process: stochastic mechanism, short time and precision of proteins self-assembling. A constructive role of entropy in the formation of a highly ordered structure out of disorder is discussed. A numerical method of a priori calculations of polypeptide structures basing on principles of bifractional folding model is presented.

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Entropy Oligopeptides Protein Conformation Protein Folding Protein Structure, Tertiary Proteins Thermodynamics Journal Article

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E M Popov. 1999. Protein folding as a nonlinear nonequilibrium thermodynamic process.. https://doi.org/10.1080/15216549900201473

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