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PubMed · 10204194

Dose response studies: how do we make them conclusive?

A Källén·P Larsson
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Abstract

In this paper we discuss how to make meaningful use of a dose response study. It is argued that concepts like the minimal effective dose are not clinically meaningful and that the purpose of a dose response study should be to identify the drug potency in relation to a known active control. We also discuss various ways of carrying out the analysis.

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Dose-Response Relationship, DrugDrug EvaluationHumansPharmaceutical PreparationsPharmacologyClinical TrialJournal ArticleRandomized Controlled TrialReview

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BibTeXRIS

A Källén, P Larsson. 1999-03-30. Dose response studies: how do we make them conclusive?. https://doi.org/10.1002/(sici)1097-0258(19990330)18%3A6%3C629%3A%3Aaid-sim72%3E3.0.co%3B2-y

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