PubMed · 10217085
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A Shuper, A Gutman, M Mimouni. 1999-04-10. Intractable epilepsy.. https://doi.org/10.1016/s0140-6736(98)11444-7
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BACKGROUND: The term "Castleman's disease" (angiofollicular lymph node hyperplasia) comprises a heterogeneous clinicopathologic entity among lymphoproliferative disorders. CASE REPORT: We present a rare case with retroperitoneal manifestations, and discuss several aspects of diagnosis, differential diagnosis, the clinical course and therapy of the disease. Finally, we summarize the actual knowledge about the pathogenesis of Castleman's disease.
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Three women, two aged 63 and one aged 47 years, developed serious abdominal pains and nausea during and/or years after treatment for metastasized lobular mammary carcinoma. These symptoms were due to jejunal tumour with perforation, sigmoid and hepatic metastases and perforated gastric metastases, respectively. After surgical treatment of the affected part of the gastrointestinal tract, the patients survived for a number of months without abdominal symptoms. Infiltrating lobular mammary carcinoma is more often associated with gastrointestinal metastases than infiltrating ductal mammary carcinoma. Progressive abdominal symptoms attributable to such metastases constitute an indication for a change of the systemic treatment. In case of insufficient effect of this treatment, and in acute situations, surgical treatment may result in protracted palliation.