Tumor-induced immunosuppression.

H Friedman; S Specter; M Watanabe; S H Pan

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PubMed · 102206

Tumor-induced immunosuppression.

H Friedman·S Specter·M Watanabe·S H Pan

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Abstract

Three tumor systems, including a mastocytoma, plasmacytomas, and a leukemia-lymphoma were studied for their ability to modify humoral immunity to sheep erythrocytes both in vivo and in vitro. All tumors resulted in a depression of the hemolytic antibody plaque-forming cell response in susceptible mice. These studies indicated that the mechanism(s) of suppression, although not fully defined, were different for each model system investigated.

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Animals Antibody Formation Cell Line Cell-Free System Friend murine leukemia virus Immunosuppression Therapy Immunosuppressive Agents Leukemia, Experimental Mast-Cell Sarcoma Mice Mice, Inbred Strains Neoplasms, Experimental Plasmacytoma Journal Article

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H Friedman, S Specter, M Watanabe, S H Pan. 1978. Tumor-induced immunosuppression.. https://pubmed.ncbi.nlm.nih.gov/102206/

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