Network contraction model for cell translocation and retrograde flow.

A B Verkhovsky; T M Svitkina; G G Borisy

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PubMed · 10320940

Network contraction model for cell translocation and retrograde flow.

A B Verkhovsky·T M Svitkina·G G Borisy

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Abstract

Kinetic and structural analysis of the actin-myosin II system in mammalian fibroblasts and fish epidermal keratocytes suggests that the cell's motility machinery arises behind the leading edge in the form of myosin filament clusters immersed in an actin filament network. We discuss how the contraction of this actin-myosin II network is related to the formation of actin-myosin filament bundles, cell translocation and retrograde flow.

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Actins Cell Movement Models, Biological Myosins Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.Review

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A B Verkhovsky, T M Svitkina, G G Borisy. 1999. Network contraction model for cell translocation and retrograde flow.. https://pubmed.ncbi.nlm.nih.gov/10320940/

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