PubMed · 10322146
Peripheral T cell survival.
Abstract
T cell survival in the periphery is an active process, depending on continuous TCR engagement by peptide-MHC complexes and/or response to environmental cytokines. Naive T cells require interactions with the MHC restricting element. The survival requirements of memory T cells are as yet insufficiently characterized, but MHC-restricted interactions are not necessary.
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A A Freitas, B Rocha. 1999. Peripheral T cell survival.. https://doi.org/10.1016/s0952-7915(99)80026-0
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