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PubMed · 1032662

Dissolution of two-component solids.

S A Shah·E L Parrott
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Abstract

The dissolution rates of compressed two-component mixtures were investigated. A good correlation between the composition of the solid and its observed dissolution rate was demonstrated by regression analysis. A model for dissolution was applied to compressed mixtures of aspirin-salicylic acid, aspirin-phenacetin, phenacetin-caffeine, and aspirin and caffeine (the last mixture complexes in solution).

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Chemistry, PharmaceuticalDensitometryDrug CombinationsModels, ChemicalPressureRegression AnalysisSolubilityTabletsJournal Article

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S A Shah, E L Parrott. 1976. Dissolution of two-component solids.. https://doi.org/10.1002/jps.2600651223

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