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PubMed · 10373171

Statistics notes: variables and parameters.

D G Altman·J M Bland
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D G Altman, J M Bland. 1999-06-19. Statistics notes: variables and parameters.. https://doi.org/10.1136/bmj.318.7199.1667

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PubMed1999

[Mathematical coupling and "regression to the mean". A statistical case history].

"Regression to the mean" (RTM) is a statistical phenomenon originating from the random variation of variables rather than a true association between the variables. RTM is closely linked to mathematical coupling; unawareness of these phenomena may lead to misinterpretation of data. A study examining intracranial pressure before and after infusion of manitol is presented, in which mathematical coupling caused a highly significant (but spurious) correlation between the analysed data. The significance of RTM and mathematical coupling is demonstrated by analysis of a data set derived from random numbers.

Data Interpretation, Statistical↗