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PubMed · 10384716

Gold(I) complexes as antimicrobial agents.

F Novelli·M Recine·F Sparatore·C Juliano
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Abstract

Seven gold complexes were prepared and investigated for biocidal activity against Gram-positive and -negative bacteria, fungi and protozoa. All of them were active against the tested microorganisms with the exception of Pseudomonas aeruginosa. In many, cases minimum inhibitory concentrations (MIC) were well below 1 microgram/ml. The activity is not simply related to the gold content, but also to the nature of both the phosphine and the aminothiol to which the metal is bound.

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AnimalsAnti-Bacterial AgentsAnti-Infective AgentsAntifungal AgentsAntitrichomonal AgentsAspergillus nigerCandida albicansGoldGram-Negative BacteriaGram-Positive BacteriaMagnetic Resonance SpectroscopyMicrobial Sensitivity TestsOrganometallic CompoundsTrichomonasJournal ArticleResearch Support, Non-U.S. Gov't

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F Novelli, M Recine, F Sparatore, C Juliano. 1999-04-30. Gold(I) complexes as antimicrobial agents.. https://doi.org/10.1016/s0014-827x(99)00019-1

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