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PubMed · 10407403

Microfluidic devices for DNA analysis.

D J Ehrlich·P Matsudaira
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Abstract

Microfabricated electrophoresis devices allow us to perform short-tandem-repeat genotyping assays in under 2 min and sequence single-stranded DNA in under 15 min. This is 10-100 times faster than standard slab-gel and capillary systems. The microdevice format is the natural extension of 100 years of gradual improvements to electrophoresis but operates in an almost-perfect way, limited only by the sieving medium.

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Acrylic ResinsAutomationBase SequenceDNAElectrophoresisMolecular Sequence DataSequence Analysis, DNATandem Repeat SequencesPolyacrylamidesJournal ArticleResearch Support, U.S. Gov't, Non-P.H.S.Research Support, U.S. Gov't, P.H.S.

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D J Ehrlich, P Matsudaira. 1999. Microfluidic devices for DNA analysis.. https://doi.org/10.1016/s0167-7799(99)01310-4

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