Mapping regulatory networks in microbial cells.

R A VanBogelen; K D Greis; R M Blumenthal; T H Tani; R G Matthews

doi:10.1016/s0966-842x(99)01540-1

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PubMed · 10431205

Mapping regulatory networks in microbial cells.

R A VanBogelen·K D Greis·R M Blumenthal·T H Tani·R G Matthews

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Abstract

Genome sequences are the blueprints of diverse life forms but they reveal little information about how cells make coherent responses to environmental changes. The combined use of gene fusions, gene chips, 2-D polyacrylamide gel electrophoresis, mass spectrometry and 'old-fashioned' microbial physiology will provide the means to reveal a cell's regulatory networks and how those networks are integrated.

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Bacteria Computational Biology Databases, Factual Electrophoresis, Gel, Two-Dimensional Gene Expression Regulation, Bacterial Genome, Bacterial Mass Spectrometry Oligonucleotide Array Sequence Analysis Protein Biosynthesis Transcription, Genetic Journal Article Research Support, U.S. Gov't, Non-P.H.S.Research Support, U.S. Gov't, P.H.S.Review

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R A VanBogelen, K D Greis, R M Blumenthal, T H Tani, R G Matthews. 1999. Mapping regulatory networks in microbial cells.. https://doi.org/10.1016/s0966-842x(99)01540-1

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