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PubMed · 10431961

Delayed toxidromes.

G M Bosse·N J Matyunas
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Abstract

Some toxins do not result in clinical manifestations until several hours after exposure. This article reviews those agents that may cause delayed-onset toxicity. They are organized into four classes: specific pharmaceuticals, biologicals, pharmaceutical dosage forms, and chemicals. There are five basic mechanisms for delayed toxicity: delayed absorption, distribution factors, metabolic factors, cellular and organ capacity effects, and unknown. Scientific evidence for delayed-onset of effects varies considerably among the individual toxins.

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AcetaminophenAnalgesics, Non-NarcoticAntidepressive Agents, TricyclicAstemizoleDosage FormsDrug OverdoseHistamine H1 AntagonistsHumansHydrofluoric AcidHypoglycemic AgentsInsecticidesIronMethanolMonoamine Oxidase InhibitorsMushroom PoisoningOrganophosphorus CompoundsPoisoningThyroxineTime FactorsJournal ArticleReview

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G M Bosse, N J Matyunas. Delayed toxidromes.. https://doi.org/10.1016/s0736-4679(99)00064-5

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