Receptor signaling: when dimerization is not enough.

G Jiang; T Hunter

doi:10.1016/s0960-9822(99)80357-1

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Receptor signaling: when dimerization is not enough.

G Jiang·T Hunter

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Abstract

Activation of receptors that signal via tyrosine kinase domains has been thought to involve receptor dimerization and transphosphorylation of juxtaposed catalytic domains. Recent results suggest things might be more complex - specific intersubunit conformational changes within a dimer can also be important.

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Animals Dimerization Models, Molecular Phosphorylation Protein Conformation Protein Structure, Quaternary Receptors, Cell Surface Receptors, Erythropoietin Signal Transduction Journal Article Review

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G Jiang, T Hunter. Receptor signaling: when dimerization is not enough.. https://doi.org/10.1016/s0960-9822(99)80357-1

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