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Theoretical development and experimental evaluation of imaging models for differential-interference-contrast microscopy.

C Preza·D L Snyder·J A Conchello
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Abstract

Imaging models for differential-interference-contrast (DIC) microscopy are presented. Two- and three-dimensional models for DIC imaging under partially coherent illumination were derived and tested by using phantom specimens viewed with several conventional DIC microscopes and quasi-monochromatic light. DIC images recorded with a CCD camera were compared with model predictions that were generated by using theoretical point-spread functions, computer-generated phantoms, and estimated imaging parameters such as bias and shear. Results show quantitative and qualitative agreement between model and data for several imaging conditions.

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Evaluation Studies as TopicForecastingLightMicroscopy, InterferenceModels, TheoreticalPhantoms, ImagingPhotographyJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.

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C Preza, D L Snyder, J A Conchello. 1999. Theoretical development and experimental evaluation of imaging models for differential-interference-contrast microscopy.. https://doi.org/10.1364/josaa.16.002185

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