Silicon synaptic conductances.

C Rasche; R J Douglas

doi:10.1023/a:1008963426194

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PubMed · 10482000

Silicon synaptic conductances.

C Rasche·R J Douglas

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Abstract

We have developed compact analog integrated circuits that simulate two synaptic excitatory conductances. A four-transistor circuit captures the dynamics of an excitatory postsynaptic current caused by a real AMPA conductance. A six-transistor circuit simulates the effects of a real voltage-dependent NMDA conductance. The postsynaptic current dynamics are modeled by a current mirror integrator with adjustable gain. The voltage dependence of the silicon NMDA conductance is realized by a differential pair. We show the operation of these silicon synaptic conductances and their integration with the silicon neuron (Mahowald and Douglas, 1991).

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Action Potentials Computers, Analog Electric Conductivity Excitatory Postsynaptic Potentials Neural Networks, Computer Neurons Receptors, AMPA Receptors, N-Methyl-D-Aspartate Silicon Synapses Transistors, Electronic Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

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C Rasche, R J Douglas. Silicon synaptic conductances.. https://doi.org/10.1023/a%3A1008963426194

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