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Amphicrine tumor.

L Mándoky
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Abstract

The term amphicrine refers to cells, and tumors, which show both exocrine and endocrine features. Author s aim was to analyse the characteristics of these neoplasms. 40 suspicious cases were reviewed. Mucin-stains (PAS, diastase-PAS, Stains-all, Alcian-blue), immunohistochemistry (antibodies against Neuron-Specific Enolase (NSE), and Chromogranin A (CGA), and electronmicroscopic studies were performed to demonstrate exocrine and/or endocrine features of the tumor cells. By means of these methods, 16 cases turned out to be amphicrine tumors. Among them, there were 4 sinonasal, 1 bronchial, 1 mediastinal, 8 gastrointestinal and 2 suprarenal gland neoplasms. In connection to the subject, a brief review is given of amphicrine tumor, regarding its etiological and pathological aspects. These tumors form a distinct clinicopathological entity and should be separated from both neuroendocrine tumors and adenocarcinomas.

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AdenocarcinomaAdrenal Gland NeoplasmsAdultAgedBronchial NeoplasmsCarcinoid TumorFemaleGastrointestinal NeoplasmsHumansKidney NeoplasmsMaleMediastinal NeoplasmsMicroscopy, ElectronMiddle AgedMucinsNeoplasms, Complex and MixedParanasal Sinus NeoplasmsCase ReportsJournal Article

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L Mándoky. 1999. Amphicrine tumor.. https://doi.org/10.1053/paor.1999.0211

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