CYP1A1.

K Kawajiri

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PubMed · 10493257

CYP1A1.

K Kawajiri

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Abstract

CYP1A1 plays an important role in the metabolism of polycyclic hydrocarbons that occur in the environment and several studies suggest that the genetic polymorphism of the gene may play a role in the predisposition to cancer. In order to evaluate the function of CYP1A1 in vivo as a host factor determinant of environmentally-caused cancers in humans, additional investigations are needed involving not only molecular epidemiological approaches in different ethnic populations but also more direct approaches such as the use of gene-targeted mice as a model system.

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Animals Cytochrome P-450 CYP1A1 Environmental Exposure Genetic Predisposition to Disease Genetics, Population Genotype Humans Mice Molecular Epidemiology Neoplasms, Experimental Phenotype Polycyclic Compounds Polymorphism, Genetic Journal Article Review

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K Kawajiri. 1999. CYP1A1.. https://pubmed.ncbi.nlm.nih.gov/10493257/

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