The continuing evolution of arterial conduits.

Abstract

Vineberg used the internal thoracic artery (ITA) to achieve indirect myocardial revascularization in 1950, and Green reported direct coronary anastomosis with an operating microscope in 1968. It was not until the early 1980s that superior 10-year patency compared with saphenous vein was established for the ITA. In 1986, Loop proved better patient survival at 10 years when the left ITA was grafted to the left anterior descending artery rather than vein in patients with triple-vessel disease having complete revascularization. Only in 1998 has Lytle shown enhanced survival with use of two ITAs over one in triple-vessel disease. This report came 4 months after a report showing no additional benefit from the second ITA. Increasingly, complex use of arterial conduits allows complete revascularization with two arterial conduits (both ITAs or one ITA and one radial artery) in most patients (with 10-year data soon to be available in the former). The T-graft configuration (ITA T-graft or radial T-graft) is highly complex and utilizes single-source inflow to the entire heart (in addition to native coronary flow), which may not provide adequate inflow and remains controversial. Although patency for the ITA is well established, this cannot be said for the radial artery (one report of 55 conduits to 5.5 years), the gastroepiploic artery (one report of 44 conduits to 7 years), or the inferior epigastric artery (one report of 154 conduits to 43 months). Long-term follow-up of each conduit and each configuration is required to prove its durability and, therefore, value in the operative management of coronary disease.