Structural and signalling molecules come together at tight junctions.

S Tsukita; M Furuse; M Itoh

doi:10.1016/s0955-0674(99)00016-2

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Structural and signalling molecules come together at tight junctions.

S Tsukita·M Furuse·M Itoh

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Abstract

Tight junctions (TJs) have been suggested to act both as barriers and fences, but lack of information on the constituents of TJ strands has hampered the direct assessment of these functions. Over the past year, our understanding of the molecular architecture of TJ strands has increased markedly and we are ready to experimentally examine how TJs are involved in their dual functions.

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Animals Carrier Proteins Cell Adhesion Molecules Guanylate Kinases Humans Junctional Adhesion Molecules Membrane Proteins Models, Biological Nucleoside-Phosphate Kinase Occludin Phosphoproteins Protein Conformation Signal Transduction Tight Junctions Zonula Occludens Proteins Zonula Occludens-1 Protein Zonula Occludens-2 Protein Journal Article Review

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S Tsukita, M Furuse, M Itoh. 1999. Structural and signalling molecules come together at tight junctions.. https://doi.org/10.1016/s0955-0674(99)00016-2

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