Structure/function studies of glycosyltransferases.

C Breton; A Imberty

doi:10.1016/s0959-440x(99)00006-8

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PubMed · 10508766

Structure/function studies of glycosyltransferases.

C Breton·A Imberty

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Abstract

Glycosyltransferases are the enzymes that synthesize oligosaccharides, polysaccharides and glycoconjugates. The analysis of the wealth of sequences that are now available in databases allowed the determination of conserved peptide motifs for each class of enzyme. Recent experimental data demonstrated their importance in donor and acceptor substrate binding and in catalysis. Fold-recognition studies provided the first models of the catalytic domains of some of these enzymes, while the first successes in glycosyltransferase crystallography are opening new routes in structural glycobiology.

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Amino Acid Sequence Animals Binding Sites Catalytic Domain Glycosyltransferases Models, Molecular Molecular Sequence Data Protein Conformation Protein Structure, Secondary Journal Article Research Support, Non-U.S. Gov't Review

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C Breton, A Imberty. 1999. Structure/function studies of glycosyltransferases.. https://doi.org/10.1016/s0959-440x(99)00006-8

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