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PubMed · 10516897

Pulmonary host defenses. Implications for therapy.

C M Mason·S Nelson
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Abstract

Pulmonary host defenses comprise a redundant system of protective mechanisms against invasion of the lungs by pathogenic microbes. The upper and lower airways are uniquely suited to contain and remove organisms that gain access to the respiratory mucosa. If the balance between host and organism is disputed, however, microbial clearance may be ineffective, and infection established. Pulmonary host defense mechanisms, which provide the basis for several current therapeutic strategies, are reviewed.

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Anti-Bacterial AgentsHumansImmunity, MucosalImmunocompetenceLung DiseasesMucociliary ClearancePulmonary Gas ExchangeRespiratory MechanicsRespiratory Tract InfectionsSensitivity and SpecificityJournal ArticleResearch Support, U.S. Gov't, P.H.S.Review

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C M Mason, S Nelson. 1999. Pulmonary host defenses. Implications for therapy.. https://doi.org/10.1016/s0272-5231(05)70229-x

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