'Identify' and 'lock in': molecular integration during synaptic target recognition.

B Hoang; A Chiba

doi:10.1007/s000180050380

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'Identify' and 'lock in': molecular integration during synaptic target recognition.

B Hoang·A Chiba

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Abstract

Synaptic target recognition is a complex molecular event. In a differentiating presynaptic terminal, relatively 'rare' molecules first detect the cell identity of the synaptic target. Subsequently, many 'common' molecules continue the process of synaptogenesis. We present a theoretical framework for understanding synaptic target recognition and discuss the features of its molecular components and their integration, drawing on the rapid progress made in recent studies.

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Animals Cadherins Drosophila Integrins Models, Neurological Motor Neurons Presynaptic Terminals Synapses Journal Article Research Support, U.S. Gov't, Non-P.H.S.Research Support, U.S. Gov't, P.H.S.Review

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B Hoang, A Chiba. 1999-08-30. 'Identify' and 'lock in': molecular integration during synaptic target recognition.. https://doi.org/10.1007/s000180050380

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