Pharmaceutical VIP: prospects and problems.

I Gozes; M Fridkinb; J M Hill; D E Brenneman

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PubMed · 10519911

Pharmaceutical VIP: prospects and problems.

I Gozes·M Fridkinb·J M Hill·D E Brenneman

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Abstract

Recently, multiple receptors for vasoactive intestinal peptide (VIP) have been molecularly cloned and our understanding of VIP chemistry and mechanisms of action has been broadened. The following review outlines the physiological effects of the hormone from growth regulation, reproduction, bronchodilation, vasodilation and immune interactions to neurotrophism. VIP-based drug design and non-invasive innovative delivery modes are discussed with emphasis on tumor diagnosis and treatment, impotence treatment and neuroprotection.

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Amino Acid Sequence Animals Humans Molecular Sequence Data Receptors, Vasoactive Intestinal Peptide Vasoactive Intestinal Peptide Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.Review

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I Gozes, M Fridkinb, J M Hill, D E Brenneman. 1999. Pharmaceutical VIP: prospects and problems.. https://pubmed.ncbi.nlm.nih.gov/10519911/

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