Dehydrophenylalanine analogues: conformational characterization.

M Z Siddiqui

doi:10.1016/s0141-8130(99)00063-x

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PubMed · 10520952

Dehydrophenylalanine analogues: conformational characterization.

M Z Siddiqui

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Abstract

Few dehydrophenylalanine (deltaPhe) analogues (X-deltaPhe-Phe-Gly-X1, X = Ac-; Boc-; Z-; X1 = OMe; OH; ONH2) of virus replication inhibiting peptide (Z-D-Phe-Phe-Gly) were synthesized, and their solution conformations were investigated by 1H NMR, UV and circular dichroism (CD) spectroscopy. Homogeneity of these analogues was also assessed by reverse phase-high performance liquid chromatography (RP-HPLC) using water-acetonitrile gradients.

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Amino Acid Sequence Circular Dichroism Magnetic Resonance Spectroscopy Models, Molecular Molecular Conformation Oligopeptides Peptides Phenylalanine Spectrophotometry, Ultraviolet Journal Article

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M Z Siddiqui. 1999. Dehydrophenylalanine analogues: conformational characterization.. https://doi.org/10.1016/s0141-8130(99)00063-x

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