Biosequence exegesis.

M S Boguski

doi:10.1126/science.286.5439.453

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PubMed · 10521334

Biosequence exegesis.

M S Boguski

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Abstract

Annotation of large-scale gene sequence data will benefit from comprehensive and consistent application of well-documented, standard analysis methods and from progressive and vigilant efforts to ensure quality and utility and to keep the annotation up to date. However, it is imperative to learn how to apply information derived from functional genomics and proteomics technologies to conceptualize and explain the behaviors of biological systems. Quantitative and dynamical models of systems behaviors will supersede the limited and static forms of single-gene annotation that are now the norm. Molecular biological epistemology will increasingly encompass both teleological and causal explanations.

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Animals Base Sequence Cloning, Molecular Computational Biology Databases, Factual Genetic Techniques Genome Genome, Human Human Genome Project Humans Molecular Biology Proteome Sequence Analysis, DNA Journal Article

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M S Boguski. 1999-10-15. Biosequence exegesis.. https://doi.org/10.1126/science.286.5439.453

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