Caspase 8: igniting the death machine.

G S Salvesen

doi:10.1016/s0969-2126(00)80048-9

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Caspase 8: igniting the death machine.

G S Salvesen

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Abstract

Intense research into the signaling pathways of apoptosis has revealed a dominant role for proteases belonging to the caspase family, which in humans has 11 members at present. Two papers in the September issue of Structure with Folding & Design have for the first time revealed the structure of the key apoptotic initiator, caspase 8.

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Animals Apoptosis Caspase 8 Caspase 9 Caspases Catalytic Domain Humans Models, Molecular Protein Conformation Signal Transduction Substrate Specificity Journal Article Review

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G S Salvesen. 1999-10-15. Caspase 8: igniting the death machine.. https://doi.org/10.1016/s0969-2126(00)80048-9

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