PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 10555449

Myocardial viability in ischemic ventricular dysfunction.

V M Gil
View original source ↗Export metadata ↓

Abstract

In this paper, some controversial points regarding myocardial its definition hibernation are discussed, including its definition (improvement in contractility versus improvement in clinical or functional status or in prognosis), the histology and pathophysiology (dedifferentiation versus cellular degeneration) and the responses to the diagnostic methods more currently utilised, stress echocardiography and myocardial perfusion scintigraphy. The predictor factors for recovering after revascularization are also discussed.

Explore related subjects

HeartHumansMyocardial IschemiaMyocardial RevascularizationMyocardial StunningTissue SurvivalVentricular DysfunctionJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

V M Gil. 1999. Myocardial viability in ischemic ventricular dysfunction.. https://pubmed.ncbi.nlm.nih.gov/10555449/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2001

Acute effects of continuous positive airway pressure on cardiac sympathetic tone in congestive heart failure.

BACKGROUND: Depressed ventricular performance and neurohormonal activation are key pathophysiological features of congestive heart failure (CHF). Although angiotensin-converting enzyme inhibitors and beta-adrenoceptor blockers exert beneficial effects in CHF, mortality remains unacceptably high, and the development of further therapeutic approaches is warranted. Recent data suggest that continuous positive airway pressure (CPAP) may be of benefit in the treatment of CHF, although the mechanism for this action is incompletely understood. METHODS AND RESULTS: In the present study, we examined the effect of short-term CPAP (10 cm H(2)O for 10 minutes) on hemodynamics (Swan Ganz catheter) and total systemic and cardiac sympathetic activity (norepinephrine spillover method) in 14 CHF patients in New York Heart Association class III. The application of CPAP was associated with a fall in cardiac output (4.8+/-0.3 to 4.4+/-0.2 L/min; P<0.05) and a significant reduction in cardiac norepinephrine spillover (370+/-58 to 299+/-55 pmol/min; P<0.05), although total systemic norepinephrine spillover was unchanged. CONCLUSION: The short-term application of CPAP results in an inhibition of cardiac sympathetic nervous activity. Further investigation into the potential value of long-term CPAP in CHF patients is warranted.

Heart↗
PubMed2001

Cardiac imaging at 4 Tesla.

Although higher magnetic field strength is a means to increase SNR in MRI, cardiac imaging has been difficult at high fields due to decreased RF penetration. Using a tailored cardiac coil constructed of two transmit surface coils with a four-element multicoil for signal reception, the authors demonstrate high-quality heart images acquired on a 4-T scanner. These images show an increase in SNR of approximately 2.5-fold over imaging at 1.5 T. This improvement in image quality can be used to increase in-plane resolution, reduce slice thickness, or reduce total scan time. Magn Reson Med 45:176-178, 2001.

Heart↗
PubMed2001

Estimation of respiration-induced noise fluctuations from undersampled multislice fMRI data.

Functional MRI time series data are known to be contaminated by highly structured noise due to physiological fluctuations. Significant components of this noise are at frequencies greater than those critically sampled in standard multislice imaging protocols and are therefore aliased into the activation spectrum, compromising the estimation of functional activations and the determination of their significance. However, in this work it is demonstrated that unaliased noise information is available in multislice data, and can be used to estimate and reduce noise due to high-frequency respiratory-related fluctuations. Magn Reson Med 45:635-644, 2001. Published 2001 Wiley-Liss, Inc.

Heart↗