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PubMed · 10592810

Screening for acyclovir-resistant herpes simplex virus isolates from clinical samples.

I W Mah·B I Kuo·H Y Wei·C H Tsai·W T Liu
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Abstract

The ID90 or ID50 values of acyclovir for the herpes simplex virus strains isolated in VGH-Taipei were determined by plaque reduction method. Twenty HSV isolates of 1980's (1980-1985) and thirty of 1990's (1990-1995) were subjected to plaque reduction assay for susceptibility test to acyclovir. There were fifteen HSV isolates of 1990's whose ID90 were higher than those of 1980's, indicating a trend of more acyclovir resistant isolates in 1990's.

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AcyclovirAnimalsAntiviral AgentsChlorocebus aethiopsDrug Resistance, MicrobialHumansSimplexvirusVero CellsJournal ArticleResearch Support, Non-U.S. Gov't

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I W Mah, B I Kuo, H Y Wei, C H Tsai, W T Liu. 1997. Screening for acyclovir-resistant herpes simplex virus isolates from clinical samples.. https://pubmed.ncbi.nlm.nih.gov/10592810/

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